Multiple Organ Dysfunction Syndrome

Nikoleta S. Kolovos

doi:10.1007/978-3-030-53363-2_36

Multiple Organ Dysfunction Syndrome

Nikoleta S. Kolovos

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

Multiple organ dysfunction syndrome (MODS) is the final common pathway that results in widespread endothelial dysfunction and organ injury. The American College of Chest Physicians/Society of Critical Care Medicine Consensus statement in 1992 describes the “multiple organ dysfunction syndrome” as a continuum of organ compromise. This chapter describes the proposed cellular mechanisms that lead to multiple organ dysfunction syndrome in response to a pathologic stimulus, delineates the individual organ system dysfunction in this setting, reviews predictors of outcomes, and offers approaches to therapeutic interventions.

Original language	English
Title of host publication	Pediatric Critical Care
Subtitle of host publication	Text and Study Guide
Publisher	Springer Science+Business Media
Pages	1085-1103
Number of pages	19
ISBN (Electronic)	9783030533632
ISBN (Print)	9783030533625
DOIs	https://doi.org/10.1007/978-3-030-53363-2_36
State	Published - Jan 1 2021

Keywords

Immunoparalysis
Macrophage activation syndrome
Multiple organ dysfunction syndrome (MODS)
Pediatric Logistic Organ Dysfunction (PELOD) score
Sepsis
Sequential multiple organ failure
Thrombocytopenia-associated multiple organ failure (TAMOF)

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10.1007/978-3-030-53363-2_36

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KW - Multiple organ dysfunction syndrome (MODS)

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KW - Sepsis

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KW - Thrombocytopenia-associated multiple organ failure (TAMOF)

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Multiple Organ Dysfunction Syndrome

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Keywords

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