Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression

Keyphrases

• Genetic Background 100%
• Kidney Disease Progression 100%
• Diabetic Kidney Disease 100%
• Single-cell RNA Sequencing (scRNA-seq) 100%
• Multimodal Single-cell 100%
• Chromatin Accessibility 100%
• Proximal Tubule 75%
• Glucocorticoid Receptor 50%
• Glucose Metabolism 50%
• Receptor-binding Domain 25%
• Transcription Factor 25%
• Type 2 Diabetes Mellitus (T2DM) 25%
• Inflammation 25%
• Kidney Function 25%
• Glucocorticoid Excess 25%
• Gene Signature 25%
• Single-nucleus RNA Sequencing 25%
• External Stimuli 25%
• Adverse Metabolic Effects 25%
• Proximal Tubule Injury 25%
• Single-cell ATAC-seq 25%
• Metabolic Memory 25%

Medicine and Dentistry

• Disease Exacerbation 100%
• Diabetic Nephropathy 100%
• Genetic Background 100%
• Glucose Metabolism 50%
• Glucocorticoid Receptor 50%
• Maturity Onset Diabetes of the Young 25%
• Kidney Function 25%
• Transcription Factors 25%
• Glucocorticoid 25%
• Binding Site 25%
• Nuclear RNA 25%
• Receptor Binding 25%

Immunology and Microbiology

• Single-Cell Sequencing 100%
• Genetic Background 100%
• Glucocorticoid 100%
• Glucose Metabolism 66%
• Kidney Function 33%
• Transcription Factors 33%
• Binding Site 33%
• Receptor Binding 33%
• Ribonucleic Acid 33%