Multifunctional analytical platform on a paper strip: Separation, preconcentration, and subattomolar detection

Abdennour Abbas; Andrew Brimer; Joseph M. Slocik; Limei Tian; Rajesh R. Naik; Srikanth Singamaneni

doi:10.1021/ac303567g

Multifunctional analytical platform on a paper strip: Separation, preconcentration, and subattomolar detection

Abdennour Abbas
, Andrew Brimer
, Joseph M. Slocik
, Limei Tian
, Rajesh R. Naik
, Srikanth Singamaneni

Research output: Contribution to journal › Article › peer-review

152 Scopus citations

Abstract

We report a plasmonic paper-based analytical platform with functional versatility and subattomolar (<10^-18 M) detection limit using surface-enhanced Raman scattering as a transduction method. The microfluidic paper-based analytical device (μPAD) is made with a lithography-free process by a simple cut and drop method. Complex samples are separated by a surface chemical gradient created by differential polyelectrolyte coating of the paper. The μPAD with a starlike shape is designed to enable liquid handling by lateral flow without microchannel patterning. This design generates a rapid capillary-driven flow capable of dragging liquid samples as well as gold nanorods into a single cellulose microfiber, thereby providing an extremely preconcentrated and optically active detection spot.

Original language	English
Pages (from-to)	3977-3983
Number of pages	7
Journal	Analytical Chemistry
Volume	85
Issue number	8
DOIs	https://doi.org/10.1021/ac303567g
State	Published - Apr 16 2013

Access to Document

10.1021/ac303567g

Cite this

@article{32d36f2ae549412d82c4a58a3842ee39,

title = "Multifunctional analytical platform on a paper strip: Separation, preconcentration, and subattomolar detection",

abstract = "We report a plasmonic paper-based analytical platform with functional versatility and subattomolar (<10-18 M) detection limit using surface-enhanced Raman scattering as a transduction method. The microfluidic paper-based analytical device (μPAD) is made with a lithography-free process by a simple cut and drop method. Complex samples are separated by a surface chemical gradient created by differential polyelectrolyte coating of the paper. The μPAD with a starlike shape is designed to enable liquid handling by lateral flow without microchannel patterning. This design generates a rapid capillary-driven flow capable of dragging liquid samples as well as gold nanorods into a single cellulose microfiber, thereby providing an extremely preconcentrated and optically active detection spot.",

author = "Abdennour Abbas and Andrew Brimer and Slocik, \{Joseph M.\} and Limei Tian and Naik, \{Rajesh R.\} and Srikanth Singamaneni",

year = "2013",

month = apr,

day = "16",

doi = "10.1021/ac303567g",

language = "English",

volume = "85",

pages = "3977--3983",

journal = "Analytical Chemistry",

issn = "0003-2700",

number = "8",

}

TY - JOUR

T1 - Multifunctional analytical platform on a paper strip

T2 - Separation, preconcentration, and subattomolar detection

AU - Abbas, Abdennour

AU - Brimer, Andrew

AU - Slocik, Joseph M.

AU - Tian, Limei

AU - Naik, Rajesh R.

AU - Singamaneni, Srikanth

PY - 2013/4/16

Y1 - 2013/4/16

N2 - We report a plasmonic paper-based analytical platform with functional versatility and subattomolar (<10-18 M) detection limit using surface-enhanced Raman scattering as a transduction method. The microfluidic paper-based analytical device (μPAD) is made with a lithography-free process by a simple cut and drop method. Complex samples are separated by a surface chemical gradient created by differential polyelectrolyte coating of the paper. The μPAD with a starlike shape is designed to enable liquid handling by lateral flow without microchannel patterning. This design generates a rapid capillary-driven flow capable of dragging liquid samples as well as gold nanorods into a single cellulose microfiber, thereby providing an extremely preconcentrated and optically active detection spot.

AB - We report a plasmonic paper-based analytical platform with functional versatility and subattomolar (<10-18 M) detection limit using surface-enhanced Raman scattering as a transduction method. The microfluidic paper-based analytical device (μPAD) is made with a lithography-free process by a simple cut and drop method. Complex samples are separated by a surface chemical gradient created by differential polyelectrolyte coating of the paper. The μPAD with a starlike shape is designed to enable liquid handling by lateral flow without microchannel patterning. This design generates a rapid capillary-driven flow capable of dragging liquid samples as well as gold nanorods into a single cellulose microfiber, thereby providing an extremely preconcentrated and optically active detection spot.

UR - https://www.scopus.com/pages/publications/84876238935

U2 - 10.1021/ac303567g

DO - 10.1021/ac303567g

M3 - Article

C2 - 23425068

AN - SCOPUS:84876238935

SN - 0003-2700

VL - 85

SP - 3977

EP - 3983

JO - Analytical Chemistry

JF - Analytical Chemistry

IS - 8

ER -

Multifunctional analytical platform on a paper strip: Separation, preconcentration, and subattomolar detection

Abstract

Access to Document

Other files and links

Fingerprint

Cite this