Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy

Andrew R. Lee; Dilraj S. Grewal; Thomas J. Cummings; Laura B. Enyedi; Nicole A. Larrier; Prithvi Mruthyunjaya

doi:10.1016/j.jaapos.2017.03.014

Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy

Andrew R. Lee, Dilraj S. Grewal, Thomas J. Cummings, Laura B. Enyedi, Nicole A. Larrier, Prithvi Mruthyunjaya

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Abstract

We report a 23-month-old patient presenting with multifocal iris melanoma who underwent plaque brachytherapy with full corneal coverage. The lesion demonstrated several high-risk clinical and histopathologic features associated with iris melanoma in adults, including growth and angle seeding. The patient has been subsequently followed for 3.5 years with no evidence of recurrence. This report demonstrates the importance of serial examination of suspected melanocytic iris lesions in very young children and the effective treatment option of globe-sparing radiation therapy.

Original language	English
Pages (from-to)	410-412
Number of pages	3
Journal	Journal of AAPOS
Volume	21
Issue number	5
DOIs	https://doi.org/10.1016/j.jaapos.2017.03.014
State	Published - Oct 2017

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10.1016/j.jaapos.2017.03.014

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title = "Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy",

abstract = "We report a 23-month-old patient presenting with multifocal iris melanoma who underwent plaque brachytherapy with full corneal coverage. The lesion demonstrated several high-risk clinical and histopathologic features associated with iris melanoma in adults, including growth and angle seeding. The patient has been subsequently followed for 3.5 years with no evidence of recurrence. This report demonstrates the importance of serial examination of suspected melanocytic iris lesions in very young children and the effective treatment option of globe-sparing radiation therapy.",

author = "Lee, {Andrew R.} and Grewal, {Dilraj S.} and Cummings, {Thomas J.} and Enyedi, {Laura B.} and Larrier, {Nicole A.} and Prithvi Mruthyunjaya",

note = "Publisher Copyright: {\textcopyright} 2017 American Association for Pediatric Ophthalmology and Strabismus",

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AU - Lee, Andrew R.

AU - Grewal, Dilraj S.

AU - Cummings, Thomas J.

AU - Enyedi, Laura B.

AU - Larrier, Nicole A.

AU - Mruthyunjaya, Prithvi

PY - 2017/10

Y1 - 2017/10

N2 - We report a 23-month-old patient presenting with multifocal iris melanoma who underwent plaque brachytherapy with full corneal coverage. The lesion demonstrated several high-risk clinical and histopathologic features associated with iris melanoma in adults, including growth and angle seeding. The patient has been subsequently followed for 3.5 years with no evidence of recurrence. This report demonstrates the importance of serial examination of suspected melanocytic iris lesions in very young children and the effective treatment option of globe-sparing radiation therapy.

AB - We report a 23-month-old patient presenting with multifocal iris melanoma who underwent plaque brachytherapy with full corneal coverage. The lesion demonstrated several high-risk clinical and histopathologic features associated with iris melanoma in adults, including growth and angle seeding. The patient has been subsequently followed for 3.5 years with no evidence of recurrence. This report demonstrates the importance of serial examination of suspected melanocytic iris lesions in very young children and the effective treatment option of globe-sparing radiation therapy.

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U2 - 10.1016/j.jaapos.2017.03.014

DO - 10.1016/j.jaapos.2017.03.014

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EP - 412

JO - Journal of AAPOS

JF - Journal of AAPOS

IS - 5

ER -

Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy

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