Abstract
Epicardial mapping (254 unipolar electrodes) of the dog heart both atria was performed to determine spatial distribution of arrhythmic events. The mapping showed that the first atrial premature depolarisation (APD) emerged from ectopic foci, it showed also specific multifocal patterns suggesting a septal source of tachycardia. The data obtained suggests that vagal stimulation (VS) induces focal ectopic APDs, that APDs and escape beats may be due to the same mechanism of spontaneous depolarization in the absence of a reset from dominant rhythm, that a single VS-induced APD is sufficient for initiation of a reentrant atrial fibrillation.
Translated title of the contribution | Multielectrode mapping study of proarrhythmic vagal effects in the dog atria |
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Original language | Russian |
Pages (from-to) | 15-40 |
Number of pages | 26 |
Journal | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk |
Volume | 83 |
Issue number | 3 |
State | Published - Mar 1997 |
Externally published | Yes |