Multidisciplinary treatment of biliary tract cancers

William G. Kraybill, Henry Lee, Joel Picus, Ganeshan Ramachandran, Marvin J. Lopez, Nancy Kucik, Robert J. Myerson

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Ninety‐six patients referred for radiation therapy to Washington University affiliated institutions with tumors of the extrahepatic biliary tree form the basis of this report. Patients were examined with regard to demographic factors, tumor primary site, presenting symptoms, methods of diagnosis, and methods of management. The median survival of all 96 patients in this series was 11 months. There was no significant difference between patients with gallbladder cancer and patients with cancer of the biliary ductal system. There was a statistically significant improvement in survival in those patients undergoing resection as management or as a component of the management of their tumors (P = 0.02). Patients receiving >4,000 cGy of radiation therapy had an improved survival compared to those patients receiving ≤4,000 cGy of radiation therapy (P = 0.003). While surgical resection improved survival for those patients undergoing removal of all gross tumor, this effect was noted especially in patients with gallbladder cancer. © Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)239-245
Number of pages7
JournalJournal of surgical oncology
Issue number4
StatePublished - Apr 1994


  • Cancer
  • Gallbladder
  • extrahepatic biliary duct
  • radiation
  • surgery


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