TY - JOUR
T1 - Multi-detector computed tomography versus endoscopic ultrasonography for the detection of pancreatic cancer
AU - Kongkam, Pradermchai
AU - Jaruvongvanich, Veeravich
AU - Ave, Khin
AU - Aniwan, Satimai
AU - Amornsawadwattana, Surachai
AU - Aso, Akira
AU - Shimizu, Shuji
AU - Kullavanijaya, Pinit
AU - Rerknimitr, Rungsun
N1 - Funding Information:
This work was supported by JSPS Core-to- Core Program, B. Asia-Africa Science Platforms and was funded in part by Grant-in-Aid No. 23256005 for Scientific Research from the Japan Society for the Promotion of Science.
Publisher Copyright:
© 2018, Medical Association of Thailand. All rights reserved.
PY - 2018/4
Y1 - 2018/4
N2 - Objective: Endoscopic ultrasonography [EUS] has been claimed to be superior to computed tomography in detecting pancreatic cancer. However, there have been only few studies comparing multi-detector computed tomography [MDCT] with EUS. This study aims to compare the detection rate of EUS with that of MDCT for pancreatic cancer. Materials and Methods: This retrospective study took place in January 2009 to January 2014 at King Chulalongkorn Memorial Hospital, Bangkok, Thailand. Patients who underwent both EUS and MDCT for suspected or known pancreatic cancer were included. Patients with insufficient data, cystic pancreatic lesion, benign masses and/or other malignant masses were excluded. Only patients with pathologically proven pancreatic ductal adenocarcinoma were included for analysis. The detection rates of EUS and MDCT for pancreatic cancer were compared. Results: Sixty-eight patients with pathologically proven pancreatic adenocarcinoma (mean age 63.2±10.9 years) were analyzed. The mean maximal diameters of lesions identified (n = 60) and missed (n = 8) by MDCT were 43.7±15.6 mm and 18.4±2.9 mm, respectively. EUS and MDCT detection rate for pancreatic cancer was 98.5% and 88.2%, respectively. In pancreatic tumors 2 cm in diameter, EUS and MDCT detection rate was 83.3% and 0%, respectively. The pancreatic tumors that were missed by EUS were associated with baseline calcified chronic pancreatitis. Conclusion: EUS had a higher detection rate than MDCT for detection of pancreatic cancer, particularly for small pancreatic tumors. However, it missed pancreatic tumor in a patient with calcified chronic pancreatitis.
AB - Objective: Endoscopic ultrasonography [EUS] has been claimed to be superior to computed tomography in detecting pancreatic cancer. However, there have been only few studies comparing multi-detector computed tomography [MDCT] with EUS. This study aims to compare the detection rate of EUS with that of MDCT for pancreatic cancer. Materials and Methods: This retrospective study took place in January 2009 to January 2014 at King Chulalongkorn Memorial Hospital, Bangkok, Thailand. Patients who underwent both EUS and MDCT for suspected or known pancreatic cancer were included. Patients with insufficient data, cystic pancreatic lesion, benign masses and/or other malignant masses were excluded. Only patients with pathologically proven pancreatic ductal adenocarcinoma were included for analysis. The detection rates of EUS and MDCT for pancreatic cancer were compared. Results: Sixty-eight patients with pathologically proven pancreatic adenocarcinoma (mean age 63.2±10.9 years) were analyzed. The mean maximal diameters of lesions identified (n = 60) and missed (n = 8) by MDCT were 43.7±15.6 mm and 18.4±2.9 mm, respectively. EUS and MDCT detection rate for pancreatic cancer was 98.5% and 88.2%, respectively. In pancreatic tumors 2 cm in diameter, EUS and MDCT detection rate was 83.3% and 0%, respectively. The pancreatic tumors that were missed by EUS were associated with baseline calcified chronic pancreatitis. Conclusion: EUS had a higher detection rate than MDCT for detection of pancreatic cancer, particularly for small pancreatic tumors. However, it missed pancreatic tumor in a patient with calcified chronic pancreatitis.
KW - EUS
KW - Endoscopic ultrasonography
KW - Endoscopic ultrasound
KW - Endosonography
KW - Pancreatic cancer
KW - Pancreatic neoplasm
KW - Solid pancreatic lesion
UR - http://www.scopus.com/inward/record.url?scp=85049127661&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85049127661
SN - 0125-2208
VL - 101
SP - S59-S65
JO - Journal of the Medical Association of Thailand
JF - Journal of the Medical Association of Thailand
IS - 4
ER -