Multi-contrast photoacoustic microscopy

S. Hu, R. Sohn, Z. H. Lu, B. Soetikno, Q. Zhong, J. Yao, K. Maslov, J. M. Arbeit, L. V. Wang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


We developed multi-contrast photoacoustic microscopy (PAM) for in vivo anatomical, functional, metabolic, and molecular imaging. This technical innovation enables comprehensive understanding of the tumor microenvironment. With multi-contrast PAM, we longitudinally determined tumor vascular anatomy, blood flow, oxygen saturation of hemoglobin, and oxygen extraction fraction.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2012
StatePublished - 2012
EventPhotons Plus Ultrasound: Imaging and Sensing 2012 - San Francisco, CA, United States
Duration: Jan 22 2012Jan 24 2012

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferencePhotons Plus Ultrasound: Imaging and Sensing 2012
Country/TerritoryUnited States
CitySan Francisco, CA


  • Hemoglobin oxygen saturation
  • Optical-resolution photoacoustic microscopy
  • Oxygen extraction fraction
  • Tumor microenvironment
  • Vascular anatomy


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