mTORC2 signaling promotes skeletal growth and bone formation in mice

Medicine and Dentistry

• Ossification 100%
• Bone Growth 100%
• Mechanistic Target of Rapamycin 100%
• Homeostasis 50%
• Limb 50%
• Bone Mass 50%
• Programmed Cell Death 50%
• Bone Development 50%
• Cancellous Bone 50%
• Osteolysis 50%
• Mesenchyme 50%
• Physiological Process 50%
• Cortical Bone 50%
• Cell Size 50%
• Mouse Embryo 50%
• Protein Serine Threonine Kinase 50%
• Protein Complex 50%
• Chondrocyte 50%
• Anabolism 50%

Biochemistry, Genetics and Molecular Biology

• Ossification 100%
• Bone Growth 100%
• Mechanistic Target of Rapamycin 100%
• Anabolism 50%
• Bone Development 50%
• Kinase 50%
• Phosphotransferase 50%
• Homeostasis 50%
• Mesenchyme 50%
• Chondrocyte 50%
• Bone Mass 50%
• Protein Complexes 50%
• Osteolysis 50%
• Physiological Process 50%
• Cell Size 50%
• Serine 50%
• Threonine 50%
• Programmed Cell Death 50%

Keyphrases

• Bone Formation 100%
• Skeletal Growth 100%
• Skeletal Bone 100%
• MTOR Complex 2 (mTORC2) 100%
• Rictor 83%
• Mammalian Target of Rapamycin (mTOR) 66%
• Skeletal Elements 33%
• Skeletal Development 16%
• Gene-deficient Mice 16%
• Protein Complex 16%
• Cell Matrix 16%
• Postnatal Mice 16%
• Chondrocyte Hypertrophy 16%
• Apoptotic Cells 16%
• Mechanical Loading 16%
• Bone Resorption 16%
• Evolutionarily Conserved 16%
• Physiological Processes 16%
• Cortical Bone 16%
• Potential Contribution 16%
• Skeletal Homeostasis 16%
• Serine-threonine Kinase 16%
• Anabolic Response 16%
• Cell Size 16%
• Mouse Embryo 16%
• Insufficient Bone 16%
• Proliferation Apoptosis 16%
• Bone Anabolism 16%
• Trabecular Bone Mass 16%
• Matrix Production 16%
• Cartilage Anlage 16%
• Skeletogenic Mesenchyme 16%