mTOR signaling in melanoma: Oncogene-induced pseudo-senescence?

George P. Souroullas, Norman E. Sharpless

Research output: Contribution to journalShort surveypeer-review

8 Scopus citations

Abstract

Oncogene-induced senescence (OIS) is thought to be a barrier to malignant transformation resulting from the strong activation of oncogenes. In this issue of Cancer Cell, Damsky and colleagues suggest activation of mTORC1 and mTORC2 is required for OIS evasion in human melanomas harboring oncogenic BRAF mutations.

Original languageEnglish
Pages (from-to)3-5
Number of pages3
JournalCancer Cell
Volume27
Issue number1
DOIs
StatePublished - 2015

Fingerprint

Dive into the research topics of 'mTOR signaling in melanoma: Oncogene-induced pseudo-senescence?'. Together they form a unique fingerprint.

Cite this