MRI of focal cortical dysplasia

B. C.P. Lee, R. E. Schmidt, G. A. Hatfield, B. Bourgeois, T. S. Park

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


We studied nine cases of focal cortical dysplasia (FCD) by MRI, with surface-rendered 3D reconstructions. One case was also examined using single-voxel proton MR spectroscopy (MRS). The histological features were reviewed and correlated with the MRI findings. The gyri affected by FCD were enlarged and the signal of the cortex was slightly increased on T1-weighted images. The gray-white junction was indistinct. Signal from the subcortical white matter was decreased on T1- and increased on T2-weighted images in most cases. Contrast enhancement was seen in two cases. Proton MRS showed a spectrum identical to that of normal brain.

Original languageEnglish
Pages (from-to)675-683
Number of pages9
Issue number10
StatePublished - 1998


  • Cortical dysplasia, focal
  • Magnetic resonance imaging
  • Magnetic resonance spectroscopy


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