Abstract
We report on a 16-year-old girl with spastic quadriplegic cerebral palsy associated with premature birth and typical periventricular leukomalacia, who had a dramatic improvement in motor function after treatment with carbidopa/levodopa. Kinematic and electromyographic analyses of reaching movements demonstrate that levodopa decreased muscle co-contraction, decreased unwanted movements, and improved her ability to maintain a steady arm posture. These findings suggest that levodopa be considered as an adjunct therapy for the treatment of spastic quadriplegic cerebral palsy.
Original language | English |
---|---|
Pages (from-to) | 662-665 |
Number of pages | 4 |
Journal | Annals of neurology |
Volume | 47 |
Issue number | 5 |
DOIs | |
State | Published - 2000 |