Morphological differences between optic disc collaterals and neovascularization on optical coherence tomography angiography

Ankur Singh, Aniruddha Agarwal, Sarakshi Mahajan, Samendra Karkhur, Ramandeep Singh, Reema Bansal, Mangat R. Dogra, Vishali Gupta

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Background: To study morphological features of optic disc venous collaterals (OVCs) and neovascularization of optic disc (NVD) on optical coherence tomography angiography (OCTA). Methods: Patients with OVCs and NVDs secondary to ischemic retinal diseases were prospectively enrolled. Multimodal imaging was performed using color fundus photography, fluorescein angiography (FA), and OCTA. Morphological evaluation of en-face structural OCT, cross-sectional and en-face OCTA was performed. Results: Twenty eyes (20 patients; OVCs: n = 10 and NVD: n = 10) were included. OVCs appeared as small, loopy vessels distinct from surrounding peripapillary capillaries on OCTA in the radial peripapillary capillary frame. NVDs appeared as a mesh of fine caliber, raised vessels best seen in the vitreous slab of OCTA. Flow signals in these vascular alterations correlated well with hyperfluorescence on FA. Conclusions: OCTA provides improved visualization of NVDs and OVCs in ischemic retinal diseases such as diabetic retinopathy and retinal vein occlusions compared to conventional FA.

Original languageEnglish
Pages (from-to)753-759
Number of pages7
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume255
Issue number4
DOIs
StatePublished - Apr 1 2017

Keywords

  • Collaterals
  • Diabetes
  • Diabetic retinopathy
  • Fundus fluorescein angiography
  • Neovascularization of disc
  • Optic nerve
  • Optical coherence tomography angiography
  • Retinal vascular disease

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