Morita-Baylis-Hillman cyclizations of arene-ruthenium-functionalized acrylamides

F. Christopher Pigge, R. Dhanya, Erik R. Hoefgen

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Enticed by metalation with a {CpRuII} fragment, N-benzyl and N-phenethyl acrylamides participate in phosphine-promoted spirocyclizations even though they are normally unreactive in Morita-Baylis-Hillman (MBH)-type transformations. A ruthenium-arene cation serves as the electrophilic reaction partner for an in situ generated enolate ion in this organometallic variation of the MBH reaction. (Chemical Equation Presented).

Original languageEnglish
Pages (from-to)2887-2890
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number16
StatePublished - Jul 2 2007


  • Arene ligands
  • Dearomatization
  • Nitrogen heterocycles
  • Ruthenium
  • Spiro compounds


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