@article{3696ce55f8c84fe498359c17d4c16d9d,
title = "Monoclonal antibodies binding data for SARS-CoV-2 proteins",
abstract = "SARS-CoV-2 pandemic opens up the curiosity of understanding the coronavirus. This demand for the development of the regent, which can be used for academic and therapeutic applications. The present data provide the biochemical characterization of synthetically developed monoclonal antibodies for the SARS-CoV-2 proteins. The antibodies from phage-displayed antibody libraries were selected with the SARS-CoV-2 proteins immobilized in microwell plates. The clones which bind to the antigen in Fab-phage ELISA were selected, and a two-point competitive phage ELISA was performed. Antibodies binding kinetic of IgGs for SARS-CoV2 proteins further carried with B.L.I. Systematic analysis of binding with different control proteins and purified SARS-CoV-2 ensured the robustness of the antibodies.",
keywords = "B.L.I., ELISA, SARS-CoV-2",
author = "Nawneet Mishra and Joan Teyra and Boytz, {Ruth Mabel} and Shane Miersch and Merritt, {Trudy N.} and Lia Cardarelli and Maryna Gorelik and Filip Mihalic and Per Jemth and Davey, {Robert A.} and Sidhu, {Sachdev S.} and Leung, {Daisy W.} and Amarasinghe, {Gaya K.}",
note = "Funding Information: We thank Dr. N. Krogan (UCSF) for providing the SARS-CoV-2 plasmids, Ylva Ivarsson for sharing the constructs (available at Addgene). This project was funded by grants #2161 to G.K.A. and S.S.S. and #2189 to S.S.S. from Emergent Ventures through the Thistledown Foundation (Canada) and the Mercatus Center at George Mason University and N.I.H. grants (P01AI120943, R01AI123926, and R01AI161374 to G.K.A.; R01AI107056 to D.W.L.) and partly by a CIHR operating grant (COVID-19 Rapid Research Funding #OV3-170649) to S.S.S. Publisher Copyright: {\textcopyright} 2022 The Authors",
year = "2022",
month = aug,
doi = "10.1016/j.dib.2022.108415",
language = "English",
volume = "43",
journal = "Data in Brief",
issn = "2352-3409",
}