Monitoring the brain: Processed electroencephalogram and peri-operative outcomes

K. E. Escallier, M. R. Nadelson, D. Zhou, M. S. Avidan

Research output: Contribution to journalReview articlepeer-review

58 Scopus citations


Summary Although the brain is the target organ of general anaesthesia, the utility of intra-operative brain monitoring remains controversial. Ideally, the incorporation of brain monitoring into routine practice would promote the maintenance of an optimal depth of anaesthesia, with an ultimate goal of avoiding the negative outcomes that have been associated with inadequate or excessive anaesthesia. A variety of processed electroencephalogram devices exist, of which the bispectral index is the most widely used, particularly in the research setting. Whether such devices prove to be useful will depend not only on their ability to influence anaesthetic management but also on whether the changes they promote can actually affect clinically important outcomes. This review highlights the evidence for the role of bispectral index monitoring, in particular, in guiding anaesthetic management and influencing clinical outcomes, specifically intra-operative awareness, measures of early recovery, mortality and neurocognitive outcomes.

Original languageEnglish
Pages (from-to)899-910
Number of pages12
Issue number8
StatePublished - Aug 2014


Dive into the research topics of 'Monitoring the brain: Processed electroencephalogram and peri-operative outcomes'. Together they form a unique fingerprint.

Cite this