Our laboratory has cultured cells from 23 patients with head and neck carcinoma and 13 patients with soft tissue sarcoma. The data suggest that, in some patients, inherent tumor cell radioresistance contributes to radiotherapy failure. This paper examines possible mechanisms that lead to increased cell survival following radiation exposure, and their potential as targets to overcome the radioresistant patient population.
|Number of pages||7|
|Journal||Seminars in Oncology|
|Issue number||4 SUPPL. 11|
|State||Published - Aug 1992|