BASIC CONCEPTS OF HYPERTROPHY AND HEART FAILURE The past three decades have witnessed a revolution in our understanding of the molecular determinants of the cardiac stress response leading to hypertrophy and heart failure. The genesis of currently held concepts was delineation of complex signaling pathways initiated by neurohormones or growth factors that cause, modify, and antagonize cardiac hypertrophy. This chapter provides an overview of some of these findings.

Original languageEnglish
Title of host publicationHeart Failure, Second Edition
PublisherCRC Press
Number of pages12
ISBN (Electronic)9781420077018
ISBN (Print)9781420076998
StatePublished - Jan 1 2012


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