Molecular Insight into Dengue Virus Pathogenesis and Its Implications for Disease Control

Michael S. Diamond, Theodore C. Pierson

Research output: Contribution to journalReview article

104 Scopus citations

Abstract

Dengue virus (DENV) is a mosquito-transmitted RNA virus that infects an estimated 390 million humans each year. Here, we review recent advances in our understanding of the biology of DENV and describe knowledge gaps that have impacted the development of effective vaccines and therapeutics.

Original languageEnglish
Pages (from-to)488-492
Number of pages5
JournalCell
Volume162
Issue number3
DOIs
StatePublished - Aug 1 2015

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