TY - JOUR
T1 - Molecular Insight into Dengue Virus Pathogenesis and Its Implications for Disease Control
AU - Diamond, Michael S.
AU - Pierson, Theodore C.
N1 - Funding Information:
This work was supported by the intramural program of the National Institute of Allergy and Infectious Diseases, the Burroughs Wellcome Fund, and NIH grants R01 AI073755 and R01 AI098723. We sincerely apologize to our colleagues whose primary studies we were unable to cite due to the limited scope and citation restrictions of this Review. M.S.D. has served as an ad hoc member of the external Scientific Advisory Board of Sanofi-Pasteur.
Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Dengue virus (DENV) is a mosquito-transmitted RNA virus that infects an estimated 390 million humans each year. Here, we review recent advances in our understanding of the biology of DENV and describe knowledge gaps that have impacted the development of effective vaccines and therapeutics.
AB - Dengue virus (DENV) is a mosquito-transmitted RNA virus that infects an estimated 390 million humans each year. Here, we review recent advances in our understanding of the biology of DENV and describe knowledge gaps that have impacted the development of effective vaccines and therapeutics.
UR - http://www.scopus.com/inward/record.url?scp=84938390836&partnerID=8YFLogxK
U2 - 10.1016/j.cell.2015.07.005
DO - 10.1016/j.cell.2015.07.005
M3 - Review article
C2 - 26232221
AN - SCOPUS:84938390836
SN - 0092-8674
VL - 162
SP - 488
EP - 492
JO - Cell
JF - Cell
IS - 3
ER -