Molecular imaging and therapy of atherosclerosis with targeted nanoparticles

Samuel A. Wickline; Anne M. Neubauer; Patrick M. Winter; Shelton D. Caruthers; Gregory M. Lanza

doi:10.1002/jmri.20866

Molecular imaging and therapy of atherosclerosis with targeted nanoparticles

Samuel A. Wickline
, Anne M. Neubauer
, Patrick M. Winter
, Shelton D. Caruthers
, Gregory M. Lanza

Research output: Contribution to journal › Review article › peer-review

190 Scopus citations

Abstract

Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site-targeted treatment with nanoparticle delivery systems.

Original language	English
Pages (from-to)	667-680
Number of pages	14
Journal	Journal of Magnetic Resonance Imaging
Volume	25
Issue number	4
DOIs	https://doi.org/10.1002/jmri.20866
State	Published - Apr 2007

Keywords

Atherosclerosis
Contrast agents
Drug therapy
Imaging
Nanotechnology

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10.1002/jmri.20866

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title = "Molecular imaging and therapy of atherosclerosis with targeted nanoparticles",

abstract = "Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site-targeted treatment with nanoparticle delivery systems.",

keywords = "Atherosclerosis, Contrast agents, Drug therapy, Imaging, Nanotechnology",

author = "Wickline, \{Samuel A.\} and Neubauer, \{Anne M.\} and Winter, \{Patrick M.\} and Caruthers, \{Shelton D.\} and Lanza, \{Gregory M.\}",

year = "2007",

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pages = "667--680",

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AU - Wickline, Samuel A.

AU - Neubauer, Anne M.

AU - Winter, Patrick M.

AU - Caruthers, Shelton D.

AU - Lanza, Gregory M.

PY - 2007/4

Y1 - 2007/4

N2 - Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site-targeted treatment with nanoparticle delivery systems.

AB - Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site-targeted treatment with nanoparticle delivery systems.

KW - Atherosclerosis

KW - Contrast agents

KW - Drug therapy

KW - Imaging

KW - Nanotechnology

UR - https://www.scopus.com/pages/publications/34047097882

U2 - 10.1002/jmri.20866

DO - 10.1002/jmri.20866

M3 - Review article

C2 - 17347992

AN - SCOPUS:34047097882

SN - 1053-1807

VL - 25

SP - 667

EP - 680

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

IS - 4

ER -

Molecular imaging and therapy of atherosclerosis with targeted nanoparticles

Abstract

Keywords

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