Molecular imaging and therapy of atherosclerosis with targeted nanoparticles

Samuel A. Wickline; Anne M. Neubauer; Patrick M. Winter; Shelton D. Caruthers; Gregory M. Lanza

doi:10.1002/jmri.20866

Molecular imaging and therapy of atherosclerosis with targeted nanoparticles

Samuel A. Wickline, Anne M. Neubauer, Patrick M. Winter, Shelton D. Caruthers, Gregory M. Lanza

Research output: Contribution to journal › Review article › peer-review

180 Scopus citations

Abstract

Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site-targeted treatment with nanoparticle delivery systems.

Original language	English
Pages (from-to)	667-680
Number of pages	14
Journal	Journal of Magnetic Resonance Imaging
Volume	25
Issue number	4
DOIs	https://doi.org/10.1002/jmri.20866
State	Published - Apr 2007

Keywords

Atherosclerosis
Contrast agents
Drug therapy
Imaging
Nanotechnology

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abstract = "Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site-targeted treatment with nanoparticle delivery systems.",

keywords = "Atherosclerosis, Contrast agents, Drug therapy, Imaging, Nanotechnology",

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AU - Winter, Patrick M.

AU - Caruthers, Shelton D.

AU - Lanza, Gregory M.

PY - 2007/4

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AB - Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site-targeted treatment with nanoparticle delivery systems.

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KW - Contrast agents

KW - Drug therapy

KW - Imaging

KW - Nanotechnology

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ER -

Molecular imaging and therapy of atherosclerosis with targeted nanoparticles

Abstract

Keywords

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