Molecular imaging and therapy of atherosclerosis with targeted nanoparticles

Samuel A. Wickline, Anne M. Neubauer, Patrick M. Winter, Shelton D. Caruthers, Gregory M. Lanza

Research output: Contribution to journalReview articlepeer-review

179 Scopus citations


Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site-targeted treatment with nanoparticle delivery systems.

Original languageEnglish
Pages (from-to)667-680
Number of pages14
JournalJournal of Magnetic Resonance Imaging
Issue number4
StatePublished - Apr 2007


  • Atherosclerosis
  • Contrast agents
  • Drug therapy
  • Imaging
  • Nanotechnology


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