Molecular detection of novel adenoviruses in fecal specimens of captive monkeys with diarrhea in China

K. Bányai, M. D. Esona, A. Liu, Y. Wang, X. Tu, B. Jiang

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Adenovirus (AdV) has been recently detected among monkeys with diarrhea in a major research primate colony in China. To better assess disease burden and epidemiology of adenoviruses in the colony, we examined the prevalence of this virus in fecal specimens by PCR using broadly reactive hexon gene-specific primers. Of the 29 strains that were characterized by sequence and phylogenetic analysis, we identified a broad spectrum of simian AdV (SAdV) types, including species SAdV-A (n=14) and HAdV-G (n=9). Six additional strains represented two genetic clusters distantly related to other known SAdVs. A better understanding of the epidemiology of SAdVs and their potential role in gastroenteritis is critical to the implementation of advanced prevention strategies against AdV infection in captive primates.

Original languageEnglish
Pages (from-to)416-419
Number of pages4
JournalVeterinary Microbiology
Volume142
Issue number3-4
DOIs
StatePublished - May 1 2010
Externally publishedYes

Keywords

  • Diagnosis
  • Gastroenteritis
  • Simian adenovirus

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