TY - JOUR
T1 - Modulation of left ventricular dilation remodeling with epicardial restraint devices in postmyocardial infarction heart failure
AU - Mann, Douglas L.
AU - Topkara, Veli K.
AU - Kondareddy, Srikanth
N1 - Funding Information:
This work was supported, in part, by research funds from the National Institutes of Health (UO1 HL084890-01 and RO1 HL58081-01, RO1 HL61543-01).
PY - 2009/12
Y1 - 2009/12
N2 - Myocardial infarction initiates progressive changes in the biology of the myocyte and nonmyocyte components of the myocardium, as well as the geometry of the left ventricle. Despite the use of evidence-based strategies to postmyocardial infarction, heart failure supervenes and is attended by an unacceptably high mortality rate. Given that left ventricular (LV) remodeling may contribute independently to disease progression, several innovative approaches have been designed to attenuate and reverse LV remodeling. This review discusses the emerging role of epicardial restraint devices in the treatment of postmyocardial cardiac remodeling.
AB - Myocardial infarction initiates progressive changes in the biology of the myocyte and nonmyocyte components of the myocardium, as well as the geometry of the left ventricle. Despite the use of evidence-based strategies to postmyocardial infarction, heart failure supervenes and is attended by an unacceptably high mortality rate. Given that left ventricular (LV) remodeling may contribute independently to disease progression, several innovative approaches have been designed to attenuate and reverse LV remodeling. This review discusses the emerging role of epicardial restraint devices in the treatment of postmyocardial cardiac remodeling.
UR - http://www.scopus.com/inward/record.url?scp=72449126259&partnerID=8YFLogxK
U2 - 10.1007/s11897-009-0032-6
DO - 10.1007/s11897-009-0032-6
M3 - Review article
C2 - 19948091
AN - SCOPUS:72449126259
SN - 1546-9530
VL - 6
SP - 229
EP - 235
JO - Current Heart Failure Reports
JF - Current Heart Failure Reports
IS - 4
ER -