Modulation of Immune Signaling and Metabolism Highlights Host and Fungal Transcriptional Responses in Mouse Models of Invasive Pulmonary Aspergillosis

Keyphrases

• Mouse Model 100%
• Gene Expression 100%
• Quantitative PCR 100%
• Transcriptional Response 100%
• Invasive Pulmonary Aspergillosis 100%
• Immune Signaling 100%
• Immunometabolism 100%
• Fumigatus 100%
• Model-Specific 100%
• Lung 50%
• Clinically Significant 50%
• Murine Model 50%
• Host-pathogen Interactions 50%
• Metabolism 50%
• Specific Genes 50%
• Fungi 50%
• Aspergillus Fumigatus 50%
• Active Disease 50%
• Secreted Proteins 50%
• Distinct Mechanism 50%
• Invasive Disease 50%
• Targeted Therapeutics 50%
• Immune-related Genes 50%
• Secretome 50%
• Deep Sequencing 50%
• Host Gene Expression 50%
• RNA-seq Technology 50%
• Immune-modulating Therapy 50%
• Post Inoculation 50%
• Fungal Genes 50%

Immunology and Microbiology

• Mouse Model 100%
• Gene Expression 100%
• Aspergillosis 100%
• Infectious Disease 66%
• Quantitative Reverse Transcription Polymerase Chain Reaction 66%
• Infection 66%
• Host-Pathogen Interaction 33%
• RNA Sequence 33%
• Aspergillus fumigatus 33%
• RNA Sequencing 33%
• Secretome 33%
• Fungal Gene 33%
• Lung 33%
• Steroid 33%