TY - JOUR
T1 - Moderating effects of music on resting state networks
AU - Kay, Benjamin P.
AU - Meng, Xiangxiang
AU - Difrancesco, Mark W.
AU - Holland, Scott K.
AU - Szaflarski, Jerzy P.
N1 - Funding Information:
This study was supported in part by NIH K23 NS052468 . Results were presented at the 17th Annual Meeting of the Organization on Human Brain Mapping in Quebec City, CA, 6/2011. The authors thank Steve Sands of Electrode Arrays for his assistance with implementing linear spatial filtering in Scan software.
PY - 2012/4/4
Y1 - 2012/4/4
N2 - Resting state networks (RSNs) are spontaneous, synchronous, low-frequency oscillations observed in the brains of subjects who are awake but at rest. A particular RSN called the default mode network (DMN) has been shown to exhibit changes associated with neurological disorders such as temporal lobe epilepsy or Alzheimer's disease. Previous studies have also found that differing experimental conditions such as eyes-open versus eyes-closed can produce measurable changes in the DMN. These condition-associated changes have the potential of confounding the measurements of changes in RSNs related to or caused by disease state(s). In this study, we use fMRI measurements of resting-state connectivity paired with EEG measurements of alpha rhythm and employ independent component analysis, undirected graphs of partial spectral coherence, and spatiotemporal regression to investigate the effect of music-listening on RSNs and the DMN in particular. We observed similar patterns of DMN connectivity in subjects who were listening to music compared with those who were not, with a trend toward a more introspective pattern of resting-state connectivity during music-listening. We conclude that music-listening is a valid condition under which the DMN can be studied.
AB - Resting state networks (RSNs) are spontaneous, synchronous, low-frequency oscillations observed in the brains of subjects who are awake but at rest. A particular RSN called the default mode network (DMN) has been shown to exhibit changes associated with neurological disorders such as temporal lobe epilepsy or Alzheimer's disease. Previous studies have also found that differing experimental conditions such as eyes-open versus eyes-closed can produce measurable changes in the DMN. These condition-associated changes have the potential of confounding the measurements of changes in RSNs related to or caused by disease state(s). In this study, we use fMRI measurements of resting-state connectivity paired with EEG measurements of alpha rhythm and employ independent component analysis, undirected graphs of partial spectral coherence, and spatiotemporal regression to investigate the effect of music-listening on RSNs and the DMN in particular. We observed similar patterns of DMN connectivity in subjects who were listening to music compared with those who were not, with a trend toward a more introspective pattern of resting-state connectivity during music-listening. We conclude that music-listening is a valid condition under which the DMN can be studied.
KW - Default mode network
KW - EEG
KW - Functional connectivity
KW - Independent component analysis
KW - fMRI
UR - http://www.scopus.com/inward/record.url?scp=84858446254&partnerID=8YFLogxK
U2 - 10.1016/j.brainres.2012.01.064
DO - 10.1016/j.brainres.2012.01.064
M3 - Article
C2 - 22365746
AN - SCOPUS:84858446254
SN - 0006-8993
VL - 1447
SP - 53
EP - 64
JO - Brain Research
JF - Brain Research
ER -