TY - JOUR
T1 - miTRATA
T2 - A web-based tool for microRNA Truncation and Tailing Analysis
AU - Patel, Parth
AU - Ramachandruni, S. Deepthi
AU - Kakrana, Atul
AU - Nakano, Mayumi
AU - Meyers, Blake C.
N1 - Publisher Copyright:
© The Author 2015. Published by Oxford University Press.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Summary: We describe miTRATA, the first web-based tool for microRNA Truncation and Tailing Analysis - the analysis of 3′ modifications of microRNAs including the loss or gain of nucleotides relative to the canonical sequence. miTRATA is implemented in Python (version 3) and employs parallel processing modules to enhance its scalability when analyzing multiple small RNA (sRNA) sequencing datasets. It utilizes miRBase, currently version 21, as a source of known microRNAs for analysis. miTRATA notifies user(s) via email to download as well as visualize the results online. miTRATA's strengths lie in (i) its biologist-focused web interface, (ii) improved scalability via parallel processing and (iii) its uniqueness as a webtool to perform microRNA truncation and tailing analysis.
AB - Summary: We describe miTRATA, the first web-based tool for microRNA Truncation and Tailing Analysis - the analysis of 3′ modifications of microRNAs including the loss or gain of nucleotides relative to the canonical sequence. miTRATA is implemented in Python (version 3) and employs parallel processing modules to enhance its scalability when analyzing multiple small RNA (sRNA) sequencing datasets. It utilizes miRBase, currently version 21, as a source of known microRNAs for analysis. miTRATA notifies user(s) via email to download as well as visualize the results online. miTRATA's strengths lie in (i) its biologist-focused web interface, (ii) improved scalability via parallel processing and (iii) its uniqueness as a webtool to perform microRNA truncation and tailing analysis.
UR - http://www.scopus.com/inward/record.url?scp=84962308407&partnerID=8YFLogxK
U2 - 10.1093/bioinformatics/btv583
DO - 10.1093/bioinformatics/btv583
M3 - Article
C2 - 26454275
AN - SCOPUS:84962308407
SN - 1367-4803
VL - 32
SP - 450
EP - 452
JO - Bioinformatics
JF - Bioinformatics
IS - 3
ER -