The availability of a large number of sequenced microbial genomes allows us to conduct systematic studies on microbial gene regulatory systems. Computational methods, using comparative genomics approaches, are powerful tools to understand their mechanisms and evolutionary history. Recent advances in computational methodology for uncovering transcriptional regulatory components and their interactions are discussed.

Original languageEnglish
Pages (from-to)149-153
Number of pages5
JournalCurrent Opinion in Microbiology
Issue number2
StatePublished - 2002


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