Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications

Pelin Yilmaz, Renzo Kottmann, Dawn Field, Rob Knight, James R. Cole, Linda Amaral-Zettler, Jack A. Gilbert, Ilene Karsch-Mizrachi, Anjanette Johnston, Guy Cochrane, Robert Vaughan, Christopher Hunter, Joonhong Park, Norman Morrison, Philippe Rocca-Serra, Peter Sterk, Manimozhiyan Arumugam, Mark Bailey, Laura Baumgartner, Bruce W. BirrenMartin J. Blaser, Vivien Bonazzi, Tim Booth, Peer Bork, Frederic D. Bushman, Pier Luigi Buttigieg, Patrick S.G. Chain, Emily Charlson, Elizabeth K. Costello, Heather Huot-Creasy, Peter Dawyndt, Todd Desantis, Noah Fierer, Jed A. Fuhrman, Rachel E. Gallery, Dirk Gevers, Richard A. Gibbs, Inigo San Gil, Antonio Gonzalez, Jeffrey I. Gordon, Robert Guralnick, Wolfgang Hankeln, Sarah Highlander, Philip Hugenholtz, Janet Jansson, Andrew L. Kau, Scott T. Kelley, Jerry Kennedy, Dan Knights, Omry Koren, Justin Kuczynski, Nikos Kyrpides, Robert Larsen, Christian L. Lauber, Teresa Legg, Ruth E. Ley, Catherine A. Lozupone, Wolfgang Ludwig, Donna Lyons, Eamonn Maguire, Barbara A. Methé, Folker Meyer, Brian Muegge, Sara Nakielny, Karen E. Nelson, Diana Nemergut, Josh D. Neufeld, Lindsay K. Newbold, Anna E. Oliver, Norman R. Pace, Giriprakash Palanisamy, Jörg Peplies, Joseph Petrosino, Lita Proctor, Elmar Pruesse, Christian Quast, Jeroen Raes, Sujeevan Ratnasingham, Jacques Ravel, David A. Relman, Susanna Assunta-Sansone, Patrick D. Schloss, Lynn Schriml, Rohini Sinha, Michelle I. Smith, Erica Sodergren, Aymé Spor, Jesse Stombaugh, James M. Tiedje, Doyle V. Ward, George M. Weinstock, Doug Wendel, Owen White, Andrew Whiteley, Andreas Wilke, Jennifer R. Wortman, Tanya Yatsunenko, Frank Oliver Glöckner

Research output: Contribution to journalReview articlepeer-review

523 Scopus citations


Here we present a standard developed by the Genomic Standards Consortium (GSC) for reporting marker gene sequences-the minimum information about a marker gene sequence (MIMARKS). We also introduce a system for describing the environment from which a biological sample originates. The 'environmental packages' apply to any genome sequence of known origin and can be used in combination with MIMARKS and other GSC checklists. Finally, to establish a unified standard for describing sequence data and to provide a single point of entry for the scientific community to access and learn about GSC checklists, we present the minimum information about any (x) sequence (MIxS). Adoption of MIxS will enhance our ability to analyze natural genetic diversity documented by massive DNA sequencing efforts from myriad ecosystems in our ever-changing biosphere.

Original languageEnglish
Pages (from-to)415-420
Number of pages6
JournalNature Biotechnology
Issue number5
StatePublished - May 2011


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