Abstract

Where the UUCG tetraloop is a loner, the GNRA tetraloop is gregarious. Where UUCG accommodate few substitutions, GNRA can accept many. GNRA often makes long-range hydrogen-bonding interactions to other RNA elements, the most famous being the tetraloop receptor. The GNRA tetraloop illustrates how RNA:RNA interactions work, while the UUCG tetraloop illustrates how RNA can be self-contained. These tiny RNAs have mighty roles in the biology of RNA!

Original languageEnglish
Pages (from-to)630-631
Number of pages2
JournalRNA
Volume21
Issue number4
DOIs
StatePublished - Apr 1 2015

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