Microwave-assisted efficient, one-pot, three-component synthesis of 3,5-disubstituted 1,2,4-oxadiazoles under solvent-free conditions

Mehdi Adib; Amin Haghighat Jahromi; Narjes Tavoosi; Mohammad Mahdavi; Hamid Reza Bijanzadeh

doi:10.1016/j.tetlet.2006.02.102

Microwave-assisted efficient, one-pot, three-component synthesis of 3,5-disubstituted 1,2,4-oxadiazoles under solvent-free conditions

Mehdi Adib
, Amin Haghighat Jahromi
, Narjes Tavoosi
, Mohammad Mahdavi
, Hamid Reza Bijanzadeh

Research output: Contribution to journal › Article › peer-review

88 Scopus citations

Abstract

A novel synthesis of 1,2,4-oxadiazoles is described from a one-pot, three-component reaction between nitriles, hydroxylamine, and aldehydes under microwave irradiation and solvent-free conditions in excellent yields.

Original language	English
Pages (from-to)	2965-2967
Number of pages	3
Journal	Tetrahedron Letters
Volume	47
Issue number	17
DOIs	https://doi.org/10.1016/j.tetlet.2006.02.102
State	Published - Apr 24 2006

Keywords

1,2,4-Oxadiazoles
Aldehydes
Microwave irradiation
One-pot, three-component reaction
Solvent-free synthesis

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10.1016/j.tetlet.2006.02.102

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@article{dc438002867b439586c49352153d6db4,

title = "Microwave-assisted efficient, one-pot, three-component synthesis of 3,5-disubstituted 1,2,4-oxadiazoles under solvent-free conditions",

abstract = "A novel synthesis of 1,2,4-oxadiazoles is described from a one-pot, three-component reaction between nitriles, hydroxylamine, and aldehydes under microwave irradiation and solvent-free conditions in excellent yields.",

keywords = "1,2,4-Oxadiazoles, Aldehydes, Microwave irradiation, One-pot, three-component reaction, Solvent-free synthesis",

author = "Mehdi Adib and Jahromi, \{Amin Haghighat\} and Narjes Tavoosi and Mohammad Mahdavi and Bijanzadeh, \{Hamid Reza\}",

note = "Funding Information: This research was supported by the Research Council of the University of Tehran as research project (6102036/1/02). ",

year = "2006",

month = apr,

day = "24",

doi = "10.1016/j.tetlet.2006.02.102",

language = "English",

volume = "47",

pages = "2965--2967",

journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Microwave-assisted efficient, one-pot, three-component synthesis of 3,5-disubstituted 1,2,4-oxadiazoles under solvent-free conditions

AU - Adib, Mehdi

AU - Jahromi, Amin Haghighat

AU - Tavoosi, Narjes

AU - Mahdavi, Mohammad

AU - Bijanzadeh, Hamid Reza

N1 - Funding Information: This research was supported by the Research Council of the University of Tehran as research project (6102036/1/02).

PY - 2006/4/24

Y1 - 2006/4/24

N2 - A novel synthesis of 1,2,4-oxadiazoles is described from a one-pot, three-component reaction between nitriles, hydroxylamine, and aldehydes under microwave irradiation and solvent-free conditions in excellent yields.

AB - A novel synthesis of 1,2,4-oxadiazoles is described from a one-pot, three-component reaction between nitriles, hydroxylamine, and aldehydes under microwave irradiation and solvent-free conditions in excellent yields.

KW - 1,2,4-Oxadiazoles

KW - Aldehydes

KW - Microwave irradiation

KW - One-pot, three-component reaction

KW - Solvent-free synthesis

UR - https://www.scopus.com/pages/publications/33645243205

U2 - 10.1016/j.tetlet.2006.02.102

DO - 10.1016/j.tetlet.2006.02.102

M3 - Article

AN - SCOPUS:33645243205

SN - 0040-4039

VL - 47

SP - 2965

EP - 2967

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 17

ER -

Microwave-assisted efficient, one-pot, three-component synthesis of 3,5-disubstituted 1,2,4-oxadiazoles under solvent-free conditions

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Keywords

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