Microvascular Angiopathic Consequences of COVID-19

Margaret Nalugo; Linda J. Schulte; Muhammad F. Masood; Mohamed A. Zayed

doi:10.3389/fcvm.2021.636843

Microvascular Angiopathic Consequences of COVID-19

Margaret Nalugo, Linda J. Schulte, Muhammad F. Masood, Mohamed A. Zayed

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

The coronavirus disease-2019 (COVID-19) pandemic has rapidly spread across the world. The disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first appeared in Wuhan, China in December, 2019. Ever increasing data is continuing to emerge about the impact of COVID-19 on cardiovascular tissue and other organ system. Clinical features associated with COVID-19 suggest that endothelial cell dysfunction and microvascular thrombosis are to a large extent contributing to resultant multi-organ complications. This review is aimed at highlighting the critical aspects associated with COVID-19 and its presumed microvascular angiopathic consequences on the cardiovascular system leading to multi-organ dysfunction.

Original language	English
Article number	636843
Journal	Frontiers in Cardiovascular Medicine
Volume	8
DOIs	https://doi.org/10.3389/fcvm.2021.636843
State	Published - Feb 2 2021

Keywords

COVID-19
angiopathy
cardiac dysfunction
micovascular disease
vascular thrombosis

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10.3389/fcvm.2021.636843

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title = "Microvascular Angiopathic Consequences of COVID-19",

abstract = "The coronavirus disease-2019 (COVID-19) pandemic has rapidly spread across the world. The disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first appeared in Wuhan, China in December, 2019. Ever increasing data is continuing to emerge about the impact of COVID-19 on cardiovascular tissue and other organ system. Clinical features associated with COVID-19 suggest that endothelial cell dysfunction and microvascular thrombosis are to a large extent contributing to resultant multi-organ complications. This review is aimed at highlighting the critical aspects associated with COVID-19 and its presumed microvascular angiopathic consequences on the cardiovascular system leading to multi-organ dysfunction.",

keywords = "COVID-19, angiopathy, cardiac dysfunction, micovascular disease, vascular thrombosis",

author = "Margaret Nalugo and Schulte, {Linda J.} and Masood, {Muhammad F.} and Zayed, {Mohamed A.}",

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AU - Nalugo, Margaret

AU - Schulte, Linda J.

AU - Masood, Muhammad F.

AU - Zayed, Mohamed A.

PY - 2021/2/2

Y1 - 2021/2/2

N2 - The coronavirus disease-2019 (COVID-19) pandemic has rapidly spread across the world. The disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first appeared in Wuhan, China in December, 2019. Ever increasing data is continuing to emerge about the impact of COVID-19 on cardiovascular tissue and other organ system. Clinical features associated with COVID-19 suggest that endothelial cell dysfunction and microvascular thrombosis are to a large extent contributing to resultant multi-organ complications. This review is aimed at highlighting the critical aspects associated with COVID-19 and its presumed microvascular angiopathic consequences on the cardiovascular system leading to multi-organ dysfunction.

AB - The coronavirus disease-2019 (COVID-19) pandemic has rapidly spread across the world. The disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first appeared in Wuhan, China in December, 2019. Ever increasing data is continuing to emerge about the impact of COVID-19 on cardiovascular tissue and other organ system. Clinical features associated with COVID-19 suggest that endothelial cell dysfunction and microvascular thrombosis are to a large extent contributing to resultant multi-organ complications. This review is aimed at highlighting the critical aspects associated with COVID-19 and its presumed microvascular angiopathic consequences on the cardiovascular system leading to multi-organ dysfunction.

KW - COVID-19

KW - angiopathy

KW - cardiac dysfunction

KW - micovascular disease

KW - vascular thrombosis

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DO - 10.3389/fcvm.2021.636843

M3 - Review article

C2 - 33604359

AN - SCOPUS:85105635360

SN - 2297-055X

VL - 8

JO - Frontiers in Cardiovascular Medicine

JF - Frontiers in Cardiovascular Medicine

M1 - 636843

ER -

Microvascular Angiopathic Consequences of COVID-19

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