TY - JOUR
T1 - Microsatellites and kinship
AU - Queller, David C.
AU - Strassmann, Joan E.
AU - Hughes, Colin R.
N1 - Funding Information:
Acknowledgements Our work on microsatellites is supported by NSF grants BSR90215114 and IBN92 1005 I. We thank 1.J.B oomsmafo r comments and D. Tautz for both comments and access to unpublished manuscripts.
PY - 1993/8
Y1 - 1993/8
N2 - Many evolutionary studies, particularly kinship studies, have been limited by the availability of segregating genetic marker loci. Microsatellites promise to alleviate these problems. Microsatellite loci are segments of DNA with very short sequence motifs repeated in tandem; their often numerous alleles differ in the number of these repeat units. They are very common in eukaryotic DNA and can be amplified by the polymerase chain reaction, which allows the use of minute or degraded DNA samples. The alleles can be scored consistently and compared unambiguously, even across different gels.
AB - Many evolutionary studies, particularly kinship studies, have been limited by the availability of segregating genetic marker loci. Microsatellites promise to alleviate these problems. Microsatellite loci are segments of DNA with very short sequence motifs repeated in tandem; their often numerous alleles differ in the number of these repeat units. They are very common in eukaryotic DNA and can be amplified by the polymerase chain reaction, which allows the use of minute or degraded DNA samples. The alleles can be scored consistently and compared unambiguously, even across different gels.
UR - https://www.scopus.com/pages/publications/0001025251
U2 - 10.1016/0169-5347(93)90256-O
DO - 10.1016/0169-5347(93)90256-O
M3 - Review article
AN - SCOPUS:0001025251
SN - 0169-5347
VL - 8
SP - 285
EP - 288
JO - Trends in Ecology and Evolution
JF - Trends in Ecology and Evolution
IS - 8
ER -