microRT: A conformal small animal irradiator

Daniel A. Low, Milos Vicic, Sasa Mutic, Perry W. Grigsby, Joseph O. Deasy, Andrew Hope

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The recent development of small-animal imaging hardware has provided functional imaging researchers with extraordinary tools for preclinical studies. However, radiation oncology studies, either tumor response or normal organ response, has been hampered by the lack of a tool for the precise irradiation of small animals. A conformal small animal irradiator based on teletherapy is proposed. The irradiator is based on a small, high-activity 192Ir source. Measurement-validated Monte Carlo dose distribution simulations have been conducted to aid in the optimization of the irradiator design. Adequate dose rates (in excess of 1 Gy min-1) are shown to be possible with adequately steep penumbra and low irradiation levels outside the irradiated fields. We are currently designing and building a prototype system.

Original languageEnglish
Title of host publication2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationMacro to Nano
Pages1365-1368
Number of pages4
StatePublished - 2004
Event2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States
Duration: Apr 15 2004Apr 18 2004

Publication series

Name2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume2

Conference

Conference2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Country/TerritoryUnited States
CityArlington, VA
Period04/15/0404/18/04

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