MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients

Keyphrases

• Dysregulated 100%
• Amyloid Precursor Protein 100%
• Human Fetal Brain 100%
• Brain Cells 100%
• Precursor Protein 100%
• MicroRNA-153 100%
• Alzheimer Patients 100%
• MiR-153 91%
• Protein Expression 41%
• 3′-untranslated Region (3′-UTR) 25%
• MicroRNA 16%
• APLP2 16%
• Brain Culture 16%
• Etiology 8%
• Protein Level 8%
• Reduced Expression 8%
• Control Specimen 8%
• Biological Pathways 8%
• Reporter Construct 8%
• Gene Regulatory Network 8%
• Novel Therapeutic Targets 8%
• AD Pathology 8%
• Bioinformatics Algorithms 8%
• Human Neurons 8%
• HeLa Cells 8%
• Functional Redundancy 8%
• Regulatory Interactions 8%
• Reporter Expression 8%
• Molecular Network 8%
• Antisense Inhibitor 8%
• Protein Paralogs 8%
• AD Patients 8%

Biochemistry, Genetics and Molecular Biology

• Amyloid Precursor Protein 100%
• MicroRNA 100%
• Protein Precursor 100%
• Protein Expression 41%
• Untranslated Region 25%
• APLP2 16%
• Antisense 8%
• Regulatory Network 8%
• Paralogy 8%
• Molecular Network 8%
• Amyloid Protein 8%
• Bioinformatics 8%
• Biological Pathway 8%