Microcarrier assisted synthesis in a longitudinal acoustic trap

Michael M. Binkley, Mingyang Cui, Mikhail Y. Berezin, J. Mark Meacham

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Our group has demonstrated antibody attachment, modification, and release performed on microcarrier particles-Protein G-terminated hollow glass spheres-acoustically-confined in a longitudinal standing bulk acoustic wave (LSBAW) trap. Pillar arrays amplify the local acoustic pressure field with a nodal pressure minimum perpendicular to the inflow direction to facilitate continuous, contactless, and low-volume synthesis of antibody conjugates.

Original languageEnglish
Title of host publication21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PublisherChemical and Biological Microsystems Society
Pages756-757
Number of pages2
ISBN (Electronic)9780692941836
StatePublished - Jan 1 2020
Event21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
Duration: Oct 22 2017Oct 26 2017

Publication series

Name21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
CountryUnited States
CitySavannah
Period10/22/1710/26/17

Keywords

  • Acoustic Microfluidics
  • Acoustic Trap
  • Antibody Conjugates
  • Self-Assembled Monolayers

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  • Cite this

    Binkley, M. M., Cui, M., Berezin, M. Y., & Mark Meacham, J. (2020). Microcarrier assisted synthesis in a longitudinal acoustic trap. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 756-757). (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017). Chemical and Biological Microsystems Society.