Microarray-based resequencing of multiple Bacillus anthracis isolates.

Michael E. Zwick; Farrell Mcafee; David J. Cutler; Timothy D. Read; Jacques Ravel; Gregory R. Bowman; Darrell R. Galloway; Alfred Mateczun

Microarray-based resequencing of multiple Bacillus anthracis isolates.

Michael E. Zwick
, Farrell Mcafee
, David J. Cutler
, Timothy D. Read
, Jacques Ravel
, Gregory R. Bowman
, Darrell R. Galloway
, Alfred Mateczun

Research output: Contribution to journal › Article › peer-review

Abstract

We used custom-designed resequencing arrays to generate 3.1 Mb of genomic sequence from a panel of 56 Bacillus anthracis strains. Sequence quality was shown to be very high by replication (discrepancy rate of 7.4 x 10(-7)) and by comparison to independently generated shotgun sequence (discrepancy rate < 2.5 x 10(-6)). Population genomics studies of microbial pathogens using rapid resequencing technologies such as resequencing arrays are critical for recognizing newly emerging or genetically engineered strains.

Original language	English
Pages (from-to)	R10
Journal	Genome biology
Volume	6
Issue number	1
State	Published - 2005

Cite this

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title = "Microarray-based resequencing of multiple Bacillus anthracis isolates.",

abstract = "We used custom-designed resequencing arrays to generate 3.1 Mb of genomic sequence from a panel of 56 Bacillus anthracis strains. Sequence quality was shown to be very high by replication (discrepancy rate of 7.4 x 10(-7)) and by comparison to independently generated shotgun sequence (discrepancy rate < 2.5 x 10(-6)). Population genomics studies of microbial pathogens using rapid resequencing technologies such as resequencing arrays are critical for recognizing newly emerging or genetically engineered strains.",

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AU - Zwick, Michael E.

AU - Mcafee, Farrell

AU - Cutler, David J.

AU - Read, Timothy D.

AU - Ravel, Jacques

AU - Bowman, Gregory R.

AU - Galloway, Darrell R.

AU - Mateczun, Alfred

PY - 2005

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N2 - We used custom-designed resequencing arrays to generate 3.1 Mb of genomic sequence from a panel of 56 Bacillus anthracis strains. Sequence quality was shown to be very high by replication (discrepancy rate of 7.4 x 10(-7)) and by comparison to independently generated shotgun sequence (discrepancy rate < 2.5 x 10(-6)). Population genomics studies of microbial pathogens using rapid resequencing technologies such as resequencing arrays are critical for recognizing newly emerging or genetically engineered strains.

AB - We used custom-designed resequencing arrays to generate 3.1 Mb of genomic sequence from a panel of 56 Bacillus anthracis strains. Sequence quality was shown to be very high by replication (discrepancy rate of 7.4 x 10(-7)) and by comparison to independently generated shotgun sequence (discrepancy rate < 2.5 x 10(-6)). Population genomics studies of microbial pathogens using rapid resequencing technologies such as resequencing arrays are critical for recognizing newly emerging or genetically engineered strains.

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M3 - Article

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AN - SCOPUS:15944384859

SN - 1474-7596

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JO - Genome biology

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Microarray-based resequencing of multiple Bacillus anthracis isolates.

Abstract

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