Mice deficient in dual oxidase maturation factors are severely hypothyroid

Keyphrases

• Hypothyroid 100%
• Maturation Promoting Factor 100%
• DUOX2 100%
• Hydrogen Peroxide 62%
• Iodide 37%
• Organification 37%
• Nicotinamide Adenine Dinucleotide Phosphate Oxidase 25%
• Congenital Hypothyroidism 25%
• DUOX1 25%
• Knockdown 12%
• Murine Model 12%
• Epitope 12%
• Isoenzymes 12%
• 125I 12%
• Cell Surface 12%
• Epithelial Cells 12%
• Invertebrates 12%
• Physiological Function 12%
• Homologous Recombination 12%
• Golgi 12%
• Iodinated 12%
• Maturation Defects 12%
• Later Life 12%
• Evolutionary 12%
• Developmental Defects 12%
• Intestinal Epithelial Cells 12%
• Normal Growth 12%
• Peroxidase-like Activity 12%
• Functional Expression 12%
• N-glycan 12%
• Reduced Survival 12%
• Immune Homeostasis 12%
• Heterozygous Mice 12%
• Human mutations 12%
• Inhibiting Activity 12%
• Thyroid Tissue 12%
• TSH Levels 12%
• Thyroid Peroxidase Antibody (TPOAb) 12%
• Normal Thyroid Function 12%
• Sole Source 12%
• Thyroid Function Parameters 12%
• DUOXA 12%
• Duox 12%

Biochemistry, Genetics and Molecular Biology

• Oxidoreductase 100%
• Maturation 100%
• Oxidase 100%
• Nicotinamide Adenine Dinucleotide Phosphate 66%
• Enzyme 33%
• Homeostasis 33%
• Isoenzyme 33%
• Homologous Recombination 33%
• Iodine-125 33%
• Thyroid Function 33%
• Peroxidase 33%
• Immunity 33%
• Hydrogen Peroxide 33%
• Thyroxine Blood Level 33%
• Thyroid Peroxidase 33%
• Polysaccharide 33%
• Evolution 33%

Immunology and Microbiology

• Maturation 100%
• Thyroid 66%
• Homeostasis 33%
• Epitope 33%
• Iodine-125 33%
• Cell Surface 33%
• Homologous Recombination 33%
• Immunity 33%
• Glycan 33%
• Hydrogen Peroxide 33%
• Thyroid Function 33%
• Thyroxine Blood Level 33%
• Evolution 33%
• Peroxidase 33%