Metastatic Ovarian Sertoli-Cell Tumor: FNA Findings With Immunohistochemistry

Brian Watson; Cary L. Siegel; Lourdes R. Ylagan

doi:10.1002/dc.10369

Metastatic Ovarian Sertoli-Cell Tumor: FNA Findings With Immunohistochemistry

Brian Watson, Cary L. Siegel, Lourdes R. Ylagan

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A malignant Sertoli cell tumor of the ovary is a rare sex-cord stromal derived neoplasm. Sertoli cell tumors account for ∼4% of Sertoli-stromal cell tumors (Hsu et al., J Histochem Cytochem 1981;29:577-580). The diagnosis of this entity by fine-needle aspiration and needle core biopsy can be difficult when the differential also includes a metastatic renal cell carcinoma, due to the overlap of both cytological and histological features. Here, we show that immunohistochemical staining on cytological material including alpha-inhibin can be used to differentiate between these two malignant tumors.

Original language	English
Pages (from-to)	283-286
Number of pages	4
Journal	Diagnostic cytopathology
Volume	29
Issue number	5
DOIs	https://doi.org/10.1002/dc.10369
State	Published - Nov 2003

Keywords

Cytology
Fine-needle aspiration
Immunohistochemistry
Sertoli cell tumor

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title = "Metastatic Ovarian Sertoli-Cell Tumor: FNA Findings With Immunohistochemistry",

abstract = "A malignant Sertoli cell tumor of the ovary is a rare sex-cord stromal derived neoplasm. Sertoli cell tumors account for ∼4% of Sertoli-stromal cell tumors (Hsu et al., J Histochem Cytochem 1981;29:577-580). The diagnosis of this entity by fine-needle aspiration and needle core biopsy can be difficult when the differential also includes a metastatic renal cell carcinoma, due to the overlap of both cytological and histological features. Here, we show that immunohistochemical staining on cytological material including alpha-inhibin can be used to differentiate between these two malignant tumors.",

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AU - Siegel, Cary L.

AU - Ylagan, Lourdes R.

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N2 - A malignant Sertoli cell tumor of the ovary is a rare sex-cord stromal derived neoplasm. Sertoli cell tumors account for ∼4% of Sertoli-stromal cell tumors (Hsu et al., J Histochem Cytochem 1981;29:577-580). The diagnosis of this entity by fine-needle aspiration and needle core biopsy can be difficult when the differential also includes a metastatic renal cell carcinoma, due to the overlap of both cytological and histological features. Here, we show that immunohistochemical staining on cytological material including alpha-inhibin can be used to differentiate between these two malignant tumors.

AB - A malignant Sertoli cell tumor of the ovary is a rare sex-cord stromal derived neoplasm. Sertoli cell tumors account for ∼4% of Sertoli-stromal cell tumors (Hsu et al., J Histochem Cytochem 1981;29:577-580). The diagnosis of this entity by fine-needle aspiration and needle core biopsy can be difficult when the differential also includes a metastatic renal cell carcinoma, due to the overlap of both cytological and histological features. Here, we show that immunohistochemical staining on cytological material including alpha-inhibin can be used to differentiate between these two malignant tumors.

KW - Cytology

KW - Fine-needle aspiration

KW - Immunohistochemistry

KW - Sertoli cell tumor

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JO - Diagnostic Cytopathology

JF - Diagnostic Cytopathology

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ER -

Metastatic Ovarian Sertoli-Cell Tumor: FNA Findings With Immunohistochemistry

Abstract

Keywords

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