@article{165125cd2eaf471fb9a8e9f38157c814,
title = "Metastasis suppressor genes",
abstract = "Metastasis is a major cause of cancer mortality. Metastasis is a complex process that requires the regulation of both metastasis-promoting and metastasis suppressor genes. The discovery of metastasis suppressor genes contributes significantly to our understanding of metastasis mechanisms and provides prognostic markers and therapeutic targets in clinical cancer management. In this review, we summarize the methods that have been used to identify metastasis suppressors and the potential clinical impact of these genes.",
keywords = "Functional genomics, Metastasis, Metastasis suppressor, Next generation sequencing, RNA interference",
author = "Jinchun Yan and Qin Yang and Qihong Huang",
note = "Funding Information: We are grateful to many colleagues who have shared insights with us during the writing of this chapter. Although we have attempted to be thorough, there may be some whose work was not cited. For that we apologize. We dedicate this chapter to the memories of our mothers, who died from cancers, and for the inspiration both still give us. Work from the Welch and Hurst laboratories has been generously funded by the National Cancer Institute (CA062168; CA087728, CA134981, CA089019), U.S. Army Medical Research and Materiel Command, the National Foundation for Cancer Research, and Susan G. Komen for the Cure. ",
year = "2013",
month = mar,
language = "English",
volume = "28",
pages = "285--292",
journal = "Histology and Histopathology",
issn = "0213-3911",
number = "3",
}