Metastasis occurring eleven years after diagnosis of human papilloma virus-related oropharyngeal squamous cell carcinoma

Jessica Ley, Tanya Wildes, Samir El-Mofty, Douglas Adkins

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Human papilloma virus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) is associated with a favourable prognosis, although approximately 20-25% of patients ultimately develop recurrent cancer. Most disease recurrence events appear within 3 years; however, long-term follow-up of reported studies are limited, and the risk of late recurrence is unknown. We present a case report of a patient who developed distant metastases of HPV-related SCC 11 years after initial diagnosis and treatment of HPV-related OPSCC. Late disease recurrence may occur after initial diagnosis of HPV-related OPSCC. This observation has implications on the appropriate duration of follow-up and surveillance of these patients.

Original languageEnglish
Article number480
Journalecancermedicalscience
Volume8
DOIs
StatePublished - Nov 13 2014

Keywords

  • Human papilloma virus
  • Oropharynx
  • P16

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