Metabolism of stromal and immune cells in health and disease

Bart Ghesquière, Brian W. Wong, Anna Kuchnio, Peter Carmeliet

Research output: Contribution to journalReview article

213 Scopus citations

Abstract

Cancer cells have been at the centre of cell metabolism research, but the metabolism of stromal and immune cells has received less attention. Nonetheless, these cells influence the progression of malignant, inflammatory and metabolic disorders. Here we discuss the metabolic adaptations of stromal and immune cells in health and disease, and highlight how metabolism determines their differentiation and function.

Original languageEnglish
Pages (from-to)167-176
Number of pages10
JournalNature
Volume511
Issue number7508
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

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    Ghesquière, B., Wong, B. W., Kuchnio, A., & Carmeliet, P. (2014). Metabolism of stromal and immune cells in health and disease. Nature, 511(7508), 167-176. https://doi.org/10.1038/nature13312