Metabolic storage diseases: Amyloidosis

Elizabeth M. Brunt, Dina G. Tiniakos

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


This article provides an overview of the current concepts in pathogenesis, epidemiology, clinical significance, and treatment options for amyloidosis. Emphasis is given to hepatic amyloidosis, which ranges from a clinically insignificant histologic curiosity to a harbinger of widespread disease accompanied by a poor prognosis. Clinical characteristics and clues to the diagnosis are discussed as well as the importance of histologic confirmation and the controversy surrounding liver biopsy.

Original languageEnglish
Pages (from-to)915-930
Number of pages16
JournalClinics in Liver Disease
Issue number4
StatePublished - Nov 2004


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