Metabolic connections during apoptotic cell engulfment

Claudia Z. Han, Kodi S. Ravichandran

Research output: Contribution to journalReview articlepeer-review

94 Scopus citations

Abstract

Billions of cells die via apoptosis every day and are swiftly removed. When a phagocyte engulfs an apoptotic cell, it essentially doubles its cellular contents, raising the question of how a phagocyte may manage the excess metabolic load. This Minireview discusses phagocyte cellular metabolism, the digestion of the ingested apoptotic cell, and the impact of these processes on engulfment.

Original languageEnglish
Pages (from-to)1442-1445
Number of pages4
JournalCell
Volume147
Issue number7
DOIs
StatePublished - Dec 23 2011

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