Mesial temporal sclerosis and temporal lobe epilepsy: MR imaging deformation-based segmentation of the hippocampus in five patients

Robert E. Hogan, Kevin E. Mark, Lei Wang, Sarang Joshi, Michael I. Miller, Richard D. Bucholz

Research output: Contribution to journalArticlepeer-review

86 Scopus citations

Abstract

In five patients with mesial temporal sclerosis, the authors verified the precision and reproducibility of hippocampal segmentations with deformation-based magnetic resonance (MR) imaging. The overall percentage overlap between automated segmentations was 92.8% (SD, 3.5%), between manual segmentations was 73.1% (SD, 9.5%), and between automated and manual segmentations was 74.8% (SD, 10.3%). Deformation-based hippocampal segmentations provided a precise method of hippocampal volume measurement in this patient population.

Original languageEnglish
Pages (from-to)291-297
Number of pages7
JournalRadiology
Volume216
Issue number1
DOIs
StatePublished - 2000

Keywords

  • Brain, volume
  • Epilepsy
  • Hippocampus
  • Magnetic resonance (MR), image processing
  • Magnetic resonance (MR), volume measurement
  • Schizophrenia

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