Menopause and the Risk of Coronary Heart Disease in Women

Janet Mohle-Boetani, Alice Whittemore, Graham A. Colditz, Walter C. Willett, Meir J. Stampfer, Bernard Rosner, Frank E. Speizer, Charles H. Hennekens

Research output: Contribution to journalLetterpeer-review

3 Scopus citations


To the Editor: The study by Colditz et al. (April 30 issue)* relating type of menopause and postmenopausal estrogen use to the risk of coronary heart disease addresses an important question with a potential effect on many women. The authors report that women who had undergone bilateral oophorectomy without subsequent estrogen replacement had an increased risk relative to premenopausal women of the same age, but that women who had had a natural menopause without estrogen replacement had no such elevated risk. Further analysis and more data are needed however, before natural menopause can be excluded as a determinant of the…

Original languageEnglish
Pages (from-to)1094-1095
Number of pages2
JournalNew England Journal of Medicine
Issue number17
StatePublished - Oct 22 1987


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