TY - JOUR
T1 - Meniscal and Articular Cartilage Predictors of Outcome After Revision ACL Reconstruction
T2 - A 6-Year Follow-up Cohort Study
AU - Wright, Rick W.
AU - Huston, Laura J.
AU - Haas, Amanda K.
AU - Pennings, Jacquelyn S.
AU - Allen, Christina R.
AU - Cooper, Daniel E.
AU - DeBerardino, Thomas M.
AU - Dunn, Warren R.
AU - Lantz, Brett A.
AU - Spindler, Kurt P.
AU - Stuart, Michael J.
AU - Albright, John P.
AU - Amendola, Annunziato
AU - Andrish, Jack T.
AU - Annunziata, Christopher C.
AU - Arciero, Robert A.
AU - Bach, Bernard R.
AU - Baker, Champ L.
AU - Bartolozzi, Arthur R.
AU - Baumgarten, Keith M.
AU - Bechler, Jeffery R.
AU - Berg, Jeffrey H.
AU - Bernas, Geoffrey A.
AU - Brockmeier, Stephen F.
AU - Brophy, Robert H.
AU - Bush-Joseph, Charles A.
AU - Butler, J. Brad
AU - Campbell, John D.
AU - Carey, James L.
AU - Carpenter, James E.
AU - Cole, Brian J.
AU - Cooper, Jonathan M.
AU - Cox, Charles L.
AU - Creighton, R. Alexander
AU - Dahm, Diane L.
AU - David, Tal S.
AU - Flanigan, David C.
AU - Frederick, Robert W.
AU - Ganley, Theodore J.
AU - Garofoli, Elizabeth A.
AU - Gatt, Charles J.
AU - Gecha, Steven R.
AU - Giffin, James Robert
AU - Hame, Sharon L.
AU - Hannafin, Jo A.
AU - Harner, Christopher D.
AU - Harris, Norman Lindsay
AU - Hechtman, Keith S.
AU - Hershman, Elliott B.
AU - Hoellrich, Rudolf G.
AU - Johnson, David C.
AU - Johnson, Timothy S.
AU - Jones, Morgan H.
AU - Kaeding, Christopher C.
AU - Kamath, Ganesh V.
AU - Klootwyk, Thomas E.
AU - Levy, Bruce A.
AU - Ma, C. Benjamin
AU - Maiers, G. Peter
AU - Marx, Robert G.
AU - Matava, Matthew J.
AU - Mathien, Gregory M.
AU - McAllister, David R.
AU - McCarty, Eric C.
AU - McCormack, Robert G.
AU - Miller, Bruce S.
AU - Nissen, Carl W.
AU - O’Neill, Daniel F.
AU - Owens, Brett D.
AU - Parker, Richard D.
AU - Purnell, Mark L.
AU - Ramappa, Arun J.
AU - Rauh, Michael A.
AU - Rettig, Arthur C.
AU - Sekiya, Jon K.
AU - Shea, Kevin G.
AU - Sherman, Orrin H.
AU - Slauterbeck, James R.
AU - Smith, Matthew V.
AU - Spang, Jeffrey T.
AU - Svoboda, LTC Steven J.
AU - Taft, Timothy N.
AU - Tenuta, Joachim J.
AU - Tingstad, Edwin M.
AU - Vidal, Armando F.
AU - Viskontas, Darius G.
AU - White, Richard A.
AU - Williams, James S.
AU - Wolcott, Michelle L.
AU - Wolf, Brian R.
AU - York, James J.
N1 - Publisher Copyright:
© 2023 The Author(s).
PY - 2023/3
Y1 - 2023/3
N2 - Background: Meniscal and chondral damage is common in the patient undergoing revision anterior cruciate ligament (ACL) reconstruction. Purpose: To determine if meniscal and/or articular cartilage pathology at the time of revision ACL surgery significantly influences a patient’s outcome at 6-year follow-up. Study Design: Cohort study; Level of evidence, 3. Methods: Patients undergoing revision ACL reconstruction were prospectively enrolled between 2006 and 2011. Data collection included baseline demographics, surgical technique, pathology, treatment, and scores from 4 validated patient-reported outcome instruments: International Knee Documentation Committee (IKDC), Knee injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Marx Activity Rating Scale. Patients were followed up at 6 years and asked to complete the identical set of outcome instruments. Regression analysis assessed the meniscal and articular cartilage pathology risk factors for clinical outcomes 6 years after revision ACL reconstruction. Results: An overall 1234 patients were enrolled (716 males, 58%; median age, 26 years). Surgeons reported the pathology at the time of revision surgery in the medial meniscus (45%), lateral meniscus (36%), medial femoral condyle (43%), lateral femoral condyle (29%), medial tibial plateau (11%), lateral tibial plateau (17%), patella (30%), and trochlea (21%). Six-year follow-up was obtained on 79% of the sample (980/1234). Meniscal pathology and articular cartilage pathology (medial femoral condyle, lateral femoral condyle, lateral tibial plateau, trochlea, and patella) were significant drivers of poorer patient-reported outcomes at 6 years (IKDC, KOOS, WOMAC, and Marx). The most consistent factors driving outcomes were having a medial meniscal excision (either before or at the time of revision surgery) and patellofemoral articular cartilage pathology. Six-year Marx activity levels were negatively affected by having either a repair/excision of the medial meniscus (odds ratio range, 1.45-1.72; P≤.04) or grade 3-4 patellar chondrosis (odds ratio, 1.72; P =.04). Meniscal pathology occurring before the index revision surgery negatively affected scores on all KOOS subscales except for sports/recreation (P <.05). Articular cartilage pathology significantly impaired all KOOS subscale scores (P <.05). Lower baseline outcome scores, higher body mass index, being a smoker, and incurring subsequent surgery all significantly increased the odds of reporting poorer clinical outcomes at 6 years. Conclusion: Meniscal and chondral pathology at the time of revision ACL reconstruction has continued significant detrimental effects on patient-reported outcomes at 6 years after revision surgery.
AB - Background: Meniscal and chondral damage is common in the patient undergoing revision anterior cruciate ligament (ACL) reconstruction. Purpose: To determine if meniscal and/or articular cartilage pathology at the time of revision ACL surgery significantly influences a patient’s outcome at 6-year follow-up. Study Design: Cohort study; Level of evidence, 3. Methods: Patients undergoing revision ACL reconstruction were prospectively enrolled between 2006 and 2011. Data collection included baseline demographics, surgical technique, pathology, treatment, and scores from 4 validated patient-reported outcome instruments: International Knee Documentation Committee (IKDC), Knee injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Marx Activity Rating Scale. Patients were followed up at 6 years and asked to complete the identical set of outcome instruments. Regression analysis assessed the meniscal and articular cartilage pathology risk factors for clinical outcomes 6 years after revision ACL reconstruction. Results: An overall 1234 patients were enrolled (716 males, 58%; median age, 26 years). Surgeons reported the pathology at the time of revision surgery in the medial meniscus (45%), lateral meniscus (36%), medial femoral condyle (43%), lateral femoral condyle (29%), medial tibial plateau (11%), lateral tibial plateau (17%), patella (30%), and trochlea (21%). Six-year follow-up was obtained on 79% of the sample (980/1234). Meniscal pathology and articular cartilage pathology (medial femoral condyle, lateral femoral condyle, lateral tibial plateau, trochlea, and patella) were significant drivers of poorer patient-reported outcomes at 6 years (IKDC, KOOS, WOMAC, and Marx). The most consistent factors driving outcomes were having a medial meniscal excision (either before or at the time of revision surgery) and patellofemoral articular cartilage pathology. Six-year Marx activity levels were negatively affected by having either a repair/excision of the medial meniscus (odds ratio range, 1.45-1.72; P≤.04) or grade 3-4 patellar chondrosis (odds ratio, 1.72; P =.04). Meniscal pathology occurring before the index revision surgery negatively affected scores on all KOOS subscales except for sports/recreation (P <.05). Articular cartilage pathology significantly impaired all KOOS subscale scores (P <.05). Lower baseline outcome scores, higher body mass index, being a smoker, and incurring subsequent surgery all significantly increased the odds of reporting poorer clinical outcomes at 6 years. Conclusion: Meniscal and chondral pathology at the time of revision ACL reconstruction has continued significant detrimental effects on patient-reported outcomes at 6 years after revision surgery.
KW - anterior cruciate ligament (ACL)
KW - knee articular cartilage
KW - meniscus
KW - outcomes
KW - revision ACL reconstruction
UR - http://www.scopus.com/inward/record.url?scp=85149153828&partnerID=8YFLogxK
U2 - 10.1177/03635465231151389
DO - 10.1177/03635465231151389
M3 - Article
C2 - 36734487
AN - SCOPUS:85149153828
SN - 0363-5465
VL - 51
SP - 605
EP - 614
JO - American Journal of Sports Medicine
JF - American Journal of Sports Medicine
IS - 3
ER -