Meningioma presenting as an intraoral mass in a patient with neurofibromatosis type 1

John D. Pfeifer, D. Ashley Hill, Carlos V. Ramos, Franz J. Wippold, Louis P. Dehner

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A 77-year-old woman with neurofibromatosis type 1 presented with ill- fitting dentures due to intraoral extension of a right temporal fossa mass. Computed tomographic scanning demonstrated that the masticator space mass bowed the zygomatic arch and remodeled the lateral orbit and maxillary sinus walls, findings that were consistent with the clinical diagnosis of a neurofibroma with possible malignant transformation. However, light microscopic, immunohistochemical, and ultrastructural examination of tissue from an incisional biopsy specimen were diagnostic of meningioma. This case illustrates thai the clinicopathologic differential diagnosis of an enlarging mass in patient with neurofibromatosis should include sporadic, unrelated neoplasms as well as tumors known to be associated with the syndrome.

Original languageEnglish
Pages (from-to)898-901
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Volume124
Issue number6
StatePublished - Jul 3 2000

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