TY - GEN
T1 - MEMS ultrasonic ejector array for electrospray mass spectrometry of biomolecules
AU - Aderogba, S.
AU - Meacham, J. M.
AU - Fernandez, F. M.
AU - Degertekin, F. L.
AU - Fedorov, A. G.
PY - 2005
Y1 - 2005
N2 - We developed a novel micromachined ultrasonic electrospray ionization (ESI) microarray which eliminates many limitations of the conventional capillary ESI technology. The proof-of-concept test results are presented and discussed. This technology has potential for operation at low voltages with wide range of solvents, capable of minimizing the required sample size and improving sample utilization, and is inherently suitable for parallel, high throughput mass spectrometric analysis of proteins mixtures of biological significance with multiplexing in the array format. Further, the ultrasonic ESI microarray can be made inexpensive to be disposable owing to its batch microfabrication using a simple process with only steps.
AB - We developed a novel micromachined ultrasonic electrospray ionization (ESI) microarray which eliminates many limitations of the conventional capillary ESI technology. The proof-of-concept test results are presented and discussed. This technology has potential for operation at low voltages with wide range of solvents, capable of minimizing the required sample size and improving sample utilization, and is inherently suitable for parallel, high throughput mass spectrometric analysis of proteins mixtures of biological significance with multiplexing in the array format. Further, the ultrasonic ESI microarray can be made inexpensive to be disposable owing to its batch microfabrication using a simple process with only steps.
UR - http://www.scopus.com/inward/record.url?scp=33845299013&partnerID=8YFLogxK
U2 - 10.1109/MMB.2005.1548380
DO - 10.1109/MMB.2005.1548380
M3 - Conference contribution
AN - SCOPUS:33845299013
SN - 0780387112
SN - 9780780387119
T3 - 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
SP - 45
EP - 48
BT - 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
T2 - 2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
Y2 - 12 May 2005 through 15 May 2005
ER -