Membrane receptors on rabbit and human pulmonary alveolar macrophages

C. C. Daughaday, S. D. Douglas

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Sheep erythrocytes sensitized with rabbit 7S anti Forssman Abs or 19S Ab and complement were used to demonstrate the presence of IgG and complement receptors on human and rabbit pulmonary alveolar macrophages. The IgG receptor was inhibited by aggregated human IgG more effectively than with free unaltered IgG. The complement receptor activity was abolished by trypsin. Preloading rabbit alveolar macrophages with latex particles resulted in a decrease in IgG receptor activity in some experiments while having no effect on complement receptor activity. The results suggest structural independence of these membrane markers.

Original languageEnglish
Pages (from-to)37-45
Number of pages9
JournalRES Journal of the Reticuloendothelial Society
Volume19
Issue number1
StatePublished - Dec 1 1976

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