Abstract
O'Neill et al. use optogenetic control of two distinct migration modes to address the question of how propelling forces are generated during adhesion-independent cell migration. They show that rearward plasma membrane flow generates tangential viscous forces at the cell-liquid interface to drive the cell forward.
Original language | English |
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Pages (from-to) | 9-22.e4 |
Journal | Developmental cell |
Volume | 46 |
Issue number | 1 |
DOIs | |
State | Published - Jul 2 2018 |
Keywords
- RhoA
- cell adhesion
- cell migration
- endocytosis
- membrane flow
- optogenetics
- signaling
- viscous forces