@article{5eb68cae4c1c4a0d8068e288a8594c30,
title = "Membrane Flow Drives an Adhesion-Independent Amoeboid Cell Migration Mode",
abstract = "O'Neill et al. use optogenetic control of two distinct migration modes to address the question of how propelling forces are generated during adhesion-independent cell migration. They show that rearward plasma membrane flow generates tangential viscous forces at the cell-liquid interface to drive the cell forward.",
keywords = "RhoA, cell adhesion, cell migration, endocytosis, membrane flow, optogenetics, signaling, viscous forces",
author = "O'Neill, {Patrick R.} and Castillo-Badillo, {Jean A.} and Xenia Meshik and Vani Kalyanaraman and Krystal Melgarejo and N. Gautam",
note = "Funding Information: This work was funded by the NIH through NIGMS grants GM069027 , GM107370 , and GM122577 . We thank Reza Ahmadian, Louis Hodgson, Carsten Schultz, Jennifer Stow, Akihisa Terakita, and Michael Bruchas for kindly providing DNA constructs. We thank Thomas O'Reilly-Pol (Washington University) for help with interpreting RNA-seq data. We thank Sean Collins (University of California, Davis) and John Royer (University of Edinburgh) for useful discussions. Funding Information: This work was funded by the NIH through NIGMS grants GM069027, GM107370, and GM122577. We thank Reza Ahmadian, Louis Hodgson, Carsten Schultz, Jennifer Stow, Akihisa Terakita, and Michael Bruchas for kindly providing DNA constructs. We thank Thomas O'Reilly-Pol (Washington University) for help with interpreting RNA-seq data. We thank Sean Collins (University of California, Davis) and John Royer (University of Edinburgh) for useful discussions.",
year = "2018",
month = jul,
day = "2",
doi = "10.1016/j.devcel.2018.05.029",
language = "English",
volume = "46",
pages = "9--22.e4",
journal = "Developmental Cell",
issn = "1534-5807",
number = "1",
}